Contributing Author: João Paulo de Aquino, MD, Pedro Rosa, MD, and Joseph J Cooper, MD
Contributing Editor: David Ross, MD, PhD and Ashley Walker, MD
Date Uploaded onto Website: August 1, 2016
Overview: The present session is designed to introduce residents to innovative neurobiological models for conceptualizing AD. We present three articles illustrating various therapeutic approaches to AD. We do not imply that the three articles we have selected are necessarily the most accurate or complete portrayal of neurobiology of AD. Rather, our goal is to use them to stimulate a discussion on the limitations of the current pharmacological treatments and discuss the rationale for new strategies, focusing on different targets along the complex signaling systems implicated in the pathogenesis of AD. We emphasize the need to think critically about ways in which ongoing translational research may transform the future of patients with AD over the next decade.
Author Affiliations: Dr. de Aquino is a resident in the Department of Psychiatry at Yale School of Medicine. Dr. Rosa is a resident in the Department of Psychiatry at the University of São Paolo Medical School. Dr. Cooper is from the Department of Psychiatry and Behavioral Neuroscience at the University of Chicago. David Ross, MD, PhD and Ashley Walker, MD are the Contributing Editors for this publication. The National Neuroscience Curriculum Initiative is a collaborative effort with AADPRT and the American Psychiatric Association (APA) Council on Medical Education and Lifelong Learning and receives support from the NIH (R25 MH10107602S1) ©National Neuroscience Curriculum Initiative.